The purpose of BIOSTEC is to bring together researchers and practitioners, including engineers, biologists, health professionals and informatics/computer scientists, interested in both theoretical advances and applications of information systems, artificial intelligence, signal processing, electronics and other engineering tools in knowledge areas related to biology and medicine. Conference Co-chairs Ana Fred, Instituto de Telecomunicações and Instituto Superior Técnico (University of Lisbon), Portugal Hugo Gamboa, Nova University of Lisbon, Portugal Keynote Speakers Sjaak Brinkkemper, Utrecht University, Netherlands Jordi Solé-Casals, Data and Signal Processing Group, University of Vic - Central University of Catalonia, Spain Peter Kharchenko, Altos Labs San Diego Institute of Science, United States Jun Xu, Nanjing Univ. of Info. Sci., China