LASCAS is the international symposium and flagship event of the IEEE Circuits and Systems Society in Latin America. Since its first edition in 2010, LASCAS has provided a high-quality exchange and networking forum for researchers, professionals, and students, gathering an international audience with experts from all over the world. This event is a space where the CAS community can present new concepts and innovative approaches, learn about new trends and solutions, and receive feedback from specialists in diverse fields. The 16th edition will take place in Bento Gonçalves, Brazil. The city is part of "Vale dos Vinhedos," a region with many wineries, making it a well-known enotourism route in Brazil. The region is 82 km square and located at the limits of Bento Gonçalves, Garibaldi, and Monte Belo do Sul cities. Bento Gonçalves is also known for its Maria Fumaça Tour. More information on how to get to the Bento Gonçalves city can be found at this link. Accepted papers will be submitted for inclusion into IEEE Xplore subject to meeting IEEE Xplore’s scope and quality requirements. Best papers will be invited to a special edition of the IEEE Transactions on Circuits and Systems I (TCAS-I) and IEEE Transactions on Circuits and Systems II (TCAS-II). The symposium will cover technical novelties and tutorial overviews on circuits and systems topics including but not limited to: Analog and Digital Signal Processing Biomedical Circuits and Systems Intelligent Sensor Systems and Internet of Things Artificial Intelligence and Smart Systems Nanoelectronics and Gigascale Systems Electronic Design Automation Circuits and Systems for Communications RF Circuits and Systems Smart Systems and Smart Manufacturing Power Systems and Power Electronic Circuits Multimedia Systems and Applications Life Science Systems and Applications Electronic Testing Fault Tolerant Circuits Nonlinear Circuits and Systems Cognitive Computing and Deep Learning Computing and Big Data Applications Organising Committee General Chairs Alexandra Zimpeck Brazil Fabian Olivera CEFET-RJ Brazil Program Chairs Guilherme Corrêa UFPEL Brazil François Rivet Univ. Bordeaux France Tutorial Chairs Guilherme Paim Univ. Lisboa Portugal Jose de la Rosa CNM-Sevilla Spain Track Chairs Analog, RF, and Mixed Signal Circuits Bernardo Leite (UFPR, Brazil) Rafaella Fiorelli (Universidad de Sevilla, Spain) Biomedical, Space, Automotive, IoT, and Applied Systems Leonardo Steinfeld (Universidad de la Republica, Uruguay) Emilie Avignon-Meseldzija (CentraleSupélec, France) Digital, Embedded and Intelligent Systems José Nacif (UFV, Brazil) Slavisa Jovanovic (Université de Lorraine, France) Power, Energy and Sensing Systems Cristina Meinhardt (UFSC, Brazil) Ricardo Galán (Universidad de Sevilla, Spain) Signal and Video Processing Bruno Zatt (UFPEL, Brazil) Wen-Hsiao Peng (National Yang Ming Chiao Tung University, Taiwan) Technology (Devices, Nano-Electronic), Design Automation, Test, Fault Tolerance, and Reliability Omar Paranaíba (UFMG, Brazil) Marcel Walter (Technical University of Munich, Germany)