ICSTCC 2025 aims to provide a unique, multidisciplinary forum, for scientists of academia and industry to discuss the state of the art and the new trends in system theory, control and computer engineering, and to present recent research results and prospects for development in this rapidly evolving area. The conference joins four previous scientific meetings hosted by University of Craiova (SINTES - International Conference on System Theory and Control), "Gheorghe Asachi" Technical University of Iaşi (SACCS - International Symposium on Automatic Control and Computer Science), "Dunărea de Jos" University of Galaţi, (SIMSIS - International Symposium on Modelling, Simulation and Identification Systems), and Politehnica University of Timișoara (CONTI – International Conference on Technical Informatics). As well as the previous editions, ICSTCC 2025 will be technically co-sponsored by IEEE Control Systems Society and the Proceedings will be submitted to IEEE Xplore Digital Library. Moreover, the proceedings of the 2013 to 2022 editions are indexed in Clarivate Analytics Web of Science. ICSTCC 2025 will feature several kinds of presentations, including invited talks, contributed papers, special sessions and contributions from industry. The outcome of ICSTCC 2025 is hoped to be an inclusive event, a comprehensive view and a better understanding of such leading research areas: automation, control systems, robotics, computers, electronics and electrical engineering. The conference will be held in Cluj-Napoca, the main city in Transylvania. With its rich historical and cultural heritage, Cluj-Napoca is an intellectual center with an active society, renowned universities, museums, theatres and eye-catching architecture.