The 12th International Conference on Astrophysics and Space Science (APSS 2026) will be held during December 4-6, 2026 in Sanya, China. APSS is an annual regular conference since 2015 and has been successfully held in Shanghai, China and Bangkok, Thailand. It covers issues on Celestial mechanics, Life sciences as related to space, Solar and stellar physics, Theoretical astrophysics, High-energy astrophysics, Particle astrophysics, etc.