The 11th International Conference on Astrophysics and Space Science (APSS 2025) will be held during December 5-7, 2025 in Sanya, China. APSS is an annual regular conference since 2015 and has been successfully held in Shanghai, China and Bangkok, Thailand. It covers issues on Celestial mechanics, Life sciences as related to space, Solar and stellar physics, Theoretical astrophysics, High-energy astrophysics, Particle astrophysics, etc. The conference is soliciting state-of-the-art research papers in the following areas of interest: Exoplanet Exploration Dark Matter and Dark Energy Black Holes and Neutron Stars Gravitational Waves Cosmology and the Early Universe Stellar Formation and Evolution High-Energy Astrophysics Magnetars and Pulsars Planetary Science and Missions Astrobiology Exploration of Mars The James Webb Space Telescope (JWST) Multimessenger Astronomy Cosmic Inflation Space Exploration and Colonization Asteroid Mining and Resource Utilization Interstellar Travel and Propulsion Small Satellites and CubeSats Extraterrestrial Geology and Atmospheres Space Debris and Orbital Management Cosmic Magnetic Fields Quantum Astrophysics Space Weather and Its Impact Artificial Intelligence in Space Science Other Related Topics